Publications by authors named "Claudio Espirito Santo"

Background And Aims: Atherosclerotic plaque fluorine-18 sodium fluoride (F-NaF) uptake on positron emission tomography with computed tomography (PET-CT) identifies active microcalcification and has been shown to correlate with clinical instability in patients with cardiovascular (CV) disease. Statin therapy promotes coronary macrocalcification over time. Our aim was to investigate rosuvastatin effect on atheroma F-NaF uptake.

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There have been several approaches to building charts for CV risk, all of which have both strengths and limitations. Identifying early organ damage provides relevant information and should be included in risk charts, although the direct relationship with risk is imprecise, variability between operators at the time to assess, and low availability in some healthcare systems, limits its use. Biomarkers, like troponin (cTns) isoforms cTnI and cTnT, a cardiac specific myocyte injury marker, have the great advantage of being relatively reproducible, more readily accessible, and applicable to different populations.

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Introduction: In the last years, the global context of medical education and Medical Residency programs in Portugal suffered substantial changes. The primary objective of this study was to evaluate and characterize medical residents ́ satisfaction with medical residency programs in Portugal and to identify features that could be improved.

Material And Methods: We utilized as model the survey Postgraduate Hospital Educational Environment Measure that has been developed in the United Kingdom and is speci cally targeted to medical residents.

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Synopsis of recent research by authors named "Claudio Espirito Santo"

  • - Claudio Espirito Santo's recent research primarily focuses on cardiovascular health, examining the effects of medications and biomarkers on atherosclerosis and cardiovascular risk.
  • - His study on rosuvastatin demonstrated its impact on atherosclerotic plaque metabolism, highlighting its role in influencing the uptake of F-NaF in PET-CT imaging, which is indicative of plaque instability.
  • - Additionally, he explored the potential of high sensitivity troponins as reliable biomarkers for assessing cardiovascular risk in primary prevention, emphasizing their advantages in clinical applicability and reproducibility across diverse populations.