Publications by authors named "Claudine Guillausseau"
Article Synopsis
- The study evaluates a new second-generation assay for measuring basal serum calcitonin (CT) in diagnosing and monitoring medullary thyroid carcinoma (MTC), suggesting it may be a viable alternative to the pentagastrin-stimulation test.
- A total of 162 patients, including those with RET proto-oncogene mutations and postoperative follow-up cases, participated, with measurements taken for both basal and Pg-stimulated CT levels.
- Results showed that while the new assay has high specificity and reduces false negatives compared to older methods, its sensitivity for detecting C-cell disease is still lower than that provided by the Pg-stimulation test.
Objective: To improve the preoperative selection for operation of patients with solitary thyroid nodules.
Design: Prospective cohort study.
Setting: University hospital, France.