Statherin-derived peptides as antifungal strategy against Candida albicans.

Objective: The aim of this in vitro study was to evaluate the effect of statherin and its naturally occurring peptides (DR9-2, DR9, GE-12, IT-32, GQ-19, IP-18) on Candida albicans metabolism and biofilm development.

Design: After the killing assay, a peptide pellicle was formed on the bottom of a polystyrene plate at the IC of each peptide. Over the peptide pellicle, Candida albicans biofilm (48 h) was grown.

Physical properties of artificial teeth after immersion in liquid disinfectant soaps.

Purpose: To evaluate the hardness, roughness and color stability of artificial teeth after immersion in liquid disinfectant soaps.

Methods: Artificial teeth (Vipi Dent Plus, ArtiPlus and Biolux) were divided into four groups (n=15), according to the type of immersion solution: distilled water/control group (DW); liquid disinfectant soap Dettol (SD); liquid disinfectant soap Protex (SP); and liquid disinfectant soap Lifebuoy (SL). The immersion cycles occurred every day, for 8 hours at room temperature in each disinfectant solution, following immersion in distilled water for 16 hours at 37°C.

Cytotoxicity of antimicrobial photodynamic inactivation on epithelial cells when co-cultured with Candida albicans.

This study assessed the cytotoxicity of antimicrobial Photodynamic Inactivation (aPDI), mediated by curcumin, using human keratinocytes co-cultured with Candida albicans. Cells and microorganisms were grown separately for 24 hours and then kept in contact for an additional 24 hours. After this period, aPDI was applied.

Peel bond strength of soft lining materials with antifungal to a denture base acrylic resin.

The effect of the addition of nystatin, miconazole, ketoconazole, chlorhexidine, and itraconazole into the soft lining materials Softone and Trusoft on their peel bond strength to a denture base acrylic resin was evaluated. Specimens of soft lining materials (n=7) were made without (control) or with the incorporation of antifungals at their minimum inhibitory concentrations to the biofilm of C. albicans and bonded to the acrylic resin.

Description of a Rat Palatal Acrylic Plate That Can Be Relined.

Purpose: The objective of this article is to describe a method to construct an intraoral acrylic device that permits a reline material to be added to the inner surface of the palatal plate.

Materials And Methods: Fifteen 60-day-old adult female rats (Rattus Norvegicus Albinus Wistar), weighing 150 to 250 g were used for this study and allocated to three groups (n = 5): G1, animals wearing a heat-polymerized acrylic resin palatal plate (Lucitone 550) for 14 days; G2, animals wearing a heat-polymerized acrylic resin palatal plate (Lucitone 550) relined with Tokuyama Rebase II for 14 days; and G3, animals maintained under the same conditions as the experimental groups, without wearing palatal plates for 14 days. The manipulation of the animals followed the guidelines of the Brazilian College of Animal Experimentation, under the approval of the animal ethics committee of the State University of Ponta Grossa.