Oral manifestations of leukemia as part of early diagnosis.

Introduction: The oral cavity can present the first clinical manifestations of leukemia, therefore; it is important to recognize their principal characteristics.

Objective: To identify oral manifestations as the first clinical signs of leukemia.

Methods: This is an integrative review, that gathered data from articles with oral manifestations of leukemia as part of its first clinical features.

Clinical features and outcomes of 134 Brazilians with acute promyelocytic leukemia who received ATRA and anthracyclines.

We report an increased incidence of high relapse risk features in 157 APL Brazilian patients. Out of 134 patients treated with ATRA and anthracyclines, only 91 (67.9%) achieved remission because 43 (32%) died during induction.