Publications by authors named "Claudia Sanz-Gonzalez"
Utility of culture and molecular methods using Allplex Bacterial Vaginosis Plus Assay (Seegene) as a tool for endometriosis, infertility and recurrent pregnancy loss diagnosis.
Diagn Microbiol Infect Dis
November 2024
Endometriosis, infertility, or recurrent pregnancy loss (RPL) are entities characterised by a decrease in Lactobacillus spp. and an increase in bacterial vaginosis-associated bacteria, (BVAV) according with 16S rRNA sequencing studies. However, the use of nucleic acid amplification tests (NAAT) as a tool for diagnosis algorithms is unknown.
View Article and Find Full Text PDFGlobally, an increase in sexually transmitted diseases worldwide has been reported, including acquired infection. Congenital syphilis is the mother-to-child transmission syphilis infection, experiencing an increase in cases returning to incidence rates of years ago. We report three cases of symptomatic congenital syphilis occurring in a tertiary-care hospital in Madrid (Spain).
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- - An increase in gonococcal infections has been observed in Europe and Spain, leading to more cases of disseminated gonococcal infection, which can include gonococcal arthritis.
- - Five cases of gonococcal arthritis were reported in a Madrid hospital between October 2022 and October 2023, primarily affecting male patients with a history of unprotected sex.
- - Advances in molecular techniques have improved the identification of culture-negative gonococcal arthritis cases and have revealed mutations linked to fluoroquinolone resistance, prompting a shift towards oral treatments.
Comparison of gradient diffusion and molecular methods using Allplex™ NG&DR assay (Seegene®) for macrolide and fluoroquinolone screening resistance in Neisseria gonorrhoeae.
Eur J Clin Microbiol Infect Dis
May 2024
Article Synopsis
- * The study compared a gradient diffusion test to a new molecular method (Allplex™ NG&DR assay) for detecting mutations linked to resistance in 100 NG isolates, finding no significant correlation for fluoroquinolone resistance but identified a high rate of S91F mutations.
- * While the molecular method showed good sensitivity (96.1%) and specificity (90.9%) for fluoroquinolone resistance, it cannot replace the gradient diffusion test for macrolides due to lack of positive results for resistance mutations.
Article Synopsis
- * Spain reported 33 cases of Shigella sonnei linked genetically to the UK strains, plus 4 cases with different strains but similar resistance.
- * These findings indicate the presence of multiple genetic groups of multidrug-resistant Shigella sonnei circulating in Spain.*
Since the beginning of the monkeypox (mpox) virus outbreak in May 2022, there has been an increase in the number of cases worldwide in the setting of sexual transmission. We have tested by real-time PCR 187 mpox patients, of which 157 patients were screened for sexually transmitted infections (STI) in 245 samples. Thirty-six pathogens were detected in 30 patients: herpes simplex virus (HSV-I/II, 12/36, 33.
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