Introduction: Epidemiological data about diabetes mellitus (DM) for sub-Saharan Africa (SSA) are scarce and the utility of glycated hemoglobin (HbA1c) to diagnose DM is uncertain in African populations with a high proportion of anemia.
Research Design And Methods: In a cross-sectional study, age-adjusted prevalence rates and predictors for DM and pre-DM were prospectively assessed by HbA1c in a semirural walk-in population of Tanzania (n=992). Predictors for DM were calculated by logistic regression.
In sub-Saharan Africa (SSA), epidemiological data for chronic kidney disease (CKD) are scarce. We conducted a prospective cross-sectional study including 952 patients in an outpatient clinic in Tanzania to explore CKD prevalence estimates and the association with cardiovascular and infectious disorders. According to KDIGO, we measured albumin-to-creatinine ratio and calculated eGFR using CKD-EPI formula.
View Article and Find Full Text PDFQuestions Under Study: The aim of this study was to evaluate risk factors and outcome of expanded-criteria donor (ECD) kidney transplants in patients with low immunological risk.
Methods: We evaluated graft survival and graft function in 265 recipients with low immunological risk defined as the absence of pretransplant donor-specific HLA antibodies.
Results: A total of 112 (42%) kidneys derived from ECD and 153 (58%) from standard-criteria donors (SCDs).
Background: Few studies have been published on the control of oral anticoagulation treatment in end stage renal disease (ESRD).
Methods: To analyse the quality of oral anticoagulation treatment control in ESRD patients treated with phenprocoumon we conducted a cohort study including all patients on chronic haemodialysis at a reference date. Data were collected retrospectively for 12 months and prospectively for 12 months preceding following the reference date.
Delayed graft function (DGF) is considered as a risk factor for renal allograft rejection, but this association might be confounded by diagnostic biases (e.g., higher biopsy frequency in patients with DGF, inclusion of clinically diagnosed rejection episodes, and limited details on the rejection phenotype).
View Article and Find Full Text PDFBackground: The American Fistula First Breakthrough Initiative currently aims for a 66% arterio-venous fistula (AVF) rate, while in the UK, best practice tariffs target AVF and arterio-venous graft (AVG) rates of 85%. The present study aims to assess whether these goals can be achieved.
Methods: We conducted a retrospective cohort study on patients who initiated haemodialysis from 1995 to 2006.
Background: Patient survival on chronic haemodialysis varies considerably among different countries and healthcare systems. To date, the survival of Swiss dialysis patients has not been analysed separately.
Methods: We consecutively enrolled 266 patients entering the chronic haemodialysis program of the University Hospital Basel between 01.
Aims: To evaluate the prevalence and predictors of airflow limitation among smokers aged > or =40 years visiting primary care practices in Switzerland, and the correlation between airflow limitation and patient-reported symptoms.
Methods: General practitioners (GPs) were invited to participate in the study via letter. Airflow limitation was measured using an EasyOne spirometer without administration of a bronchodilator, and patient-reported symptoms were evaluated using an interviewer-administered questionnaire.