Synthesis, Crystal Structures, Antimicrobial Activity, and Acute Toxicity Evaluation of Chiral Zn(II) Schiff Base Complexes.

Four mononuclear bioefficient zinc coordination complexes [Zn(NN)](ClO) (-) involving chiral bidentate Schiff base ligands have been synthesized and characterized by IR, H, and C NMR spectroscopy and mass spectrometry. X-ray crystal structures of three of the zinc complexes revealed that the zinc metal ion is hexacoordinated, exhibiting a distorted octahedral geometry where both the nitrogen atoms (NN = pyridyl and imine) of imines are coordinated to the central zinc ion. The isolated zinc complexes were evaluated for their antimicrobial activity in vitro against , , and , displaying varying levels of growth inhibition.

2-Amino-4-ferrocenyl-thia-zole.

The title compound, [Fe(CH)(CHNS)], was synthesized by the direct reaction of acetyl-ferrocene, thio-urea and resublimed iodine. The structure shows one mol-ecule in the asymmetric unit. The amino-thia-zole ring makes an angle of 14.