Publications by authors named "Claudia Maria Coelho Alves"

Aim: To investigate the association between molar incisor hypomineralization (MIH) and periodontitis in adolescents.

Methods: A population-based study was undertaken of Brazilian adolescents aged 18 and 19 years (n = 2515). MIH was assessed according to Ghanim's criteria.

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Article Synopsis
  • The study investigated how the consumption of ultra-processed foods (UPF) relates to dental caries (decayed teeth) in adolescents, considering factors like muscle mass, bone mineral density, and oral hygiene habits as potential mediators.
  • Conducted with 2,515 adolescents aged 18-19, the findings revealed that higher UPF intake directly correlates with increased dental caries, with oral hygiene habits significantly influencing this relationship.
  • The study highlights the need for improved oral hygiene education, healthy eating practices, and equitable public policies in Brazil to prevent dental caries, especially in middle and low-income communities.
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Background: Noncommunicable diseases (NCDs) predominantly affect adults, but pathophysiological changes begin decades earlier, as a continuum, with initial events apparent in adolescence. Hence, early identification and intervention are crucial for the prevention and management of NCDs. We investigated the complex network of socioeconomic, behavioral, and metabolic factors associated with the presence of NCD in Brazilian adolescents.

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Background: Excess weight (EW), especially in women of childbearing age, those who are pregnant, as well as postpartum, is a problem worldwide. Fat accumulation deregulates the inflammatory response, contributing to the development of health problems, such as periodontitis. This study investigated the association between EW and periodontitis during pregnancy.

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Objective: To analyze multiple-causal models, including socioeconomic, obesity, sugar consumption, alcohol smoking, caries, and periodontitis variables in pregnant women with early sugar exposure, obesity, and the Chronic Oral Disease Burden in their offspring around the first 1000 days of life.

Methods: The BRISA cohort study, Brazil, had two assessments: at the 22nd-25th gestational weeks and during the child's second year (n = 1141). We proposed a theoretical model exploring the association between socioeconomic and pregnancy factors (age, smoking, alcohol, sugars, obesity, periodontitis, and caries) and child's variables (sugars and overweight) with the outcome, Chronic Oral Disease Burden (latent variable deduced from visible plaque, gingivitis, and tooth decay), using structural equation modeling.

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  • The study aimed to compare various diagnostic criteria for periodontitis and assess its relationship with prematurity in mothers of infants, categorizing them into cases (gestational age <37 weeks) and controls (≥37 weeks).
  • Out of 283 mothers, periodontal evaluations indicated a wide prevalence of periodontal disease, and the gold standard for diagnosis was defined as having at least four teeth with specific probing depth and clinical attachment levels along with bleeding on probing at the same site.
  • Findings highlighted that certain diagnostic criteria, particularly involving probing depth and clinical attachment levels, showed a significant association with prematurity, supporting the importance of these measurements in identifying potential risks.
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Background: Dental eruption is part of a set of children´s somatic growth phenomena. The worldwide accepted human dental eruption chronology is still based on a small sample of European children. However, evidence points to some population variations with the eruption at least two months later in low-income countries, and local standards may be useful.

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Objective: To analyze prenatal and perinatal stressors associated with molar incisor hypomineralization (MIH) in adolescents.

Methods: Prospective cohort study collected prenatal (socioeconomic status, maternal age, number of prenatal visits, smoking, obesity during pregnancy, abortion history, gestational hypertension) and perinatal stressors (type of delivery, gestational age, birth weight, intensive care unit-ICU at birth). The outcome was MIH at 18-19 years follow-up (n = 590).

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  • Mental disorders, particularly depression, significantly impact public health in low- and middle-income countries, affecting around 80% of the population.
  • A cross-sectional study in Brazil analyzed data from the 2019 National Health Survey to identify factors associated with depression in adults, focusing on socioeconomic, lifestyle, and demographic variables.
  • The findings revealed that factors such as age, race, sex, self-reported health, certain health conditions, and lifestyle behaviors were linked to depression, suggesting that targeted public health strategies are needed to address these issues.
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This study tests the hypothesis that children 12-30 months born small for gestational age (SGA) aged are more susceptible to severe early childhood caries (S-ECC). We used data on 865 children aged 12-30 months from a prospective cohort study conducted in a city in the northeast of Brazil. The study outcome was S-ECC, defined based on the proportion of decayed tooth surfaces (cavitated or not).

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(1) Background: To investigate the grouping of obesity and insulin resistance with caries and periodontitis from a syndemic perspective through pathways of socioeconomic inequalities, smoking, alcohol, and high sugar consumption in adolescence. (2) Methods: The population-based RPS Cohort study, São Luís, Brazil, in ages 18-19 years ( = 2515) was used. The outcomes were the grouping of pbesity and Insulin Resistance Phenotype (latent variable formed by Triglycerides/HDL ratio, TyG index, and VLDL) and the Chronic Oral Disease Burden (latent variable comprising caries, bleeding on probing, probing depth ≥ 4 mm, clinical attachment level ≥ 3 mm, and visible plaque index ≥ 15%).

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Objective: Little is known about the effect of maternal immunological factors on the etiology of developmental defects of enamel (DDE). RANTES (Regulated on Activation Normal T Cell Expressed and Secreted) is a chemokine produced by fibroblasts, lymphoid and epithelial mucosa cells in response to various external stimuli. Despite its importance for embryogenesis, RANTES expression has been demonstrated in multiple diseases characterized by inflammation, tumor and immune response, and wound healing.

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The scope of this study was to analyze the factors associated with the use of dental services in Brazil. The review strategy included PubMed, SciELO, LILACS, BBO, EMBASE, Scopus, WOS and Google Scholar databases, in addition to repositories and databases of dissertations and theses. Studies were selected using the PEO (Population/Exposure/Outcomes) strategy.

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Objective: To evaluate the association between added sugar intake above the daily limit for the risk of noncommunicable diseases (NCDs) and the Chronic Oral Disease Burden in adolescents.

Methods: This was a population-based study using cross-sectional data nested to RPS Cohorts Consortium, São Luís, Brazil, from the 18-19-year-old follow-up (n = 2515). High consumption of added sugars was estimated according to the limits of the World Health Organization guidelines (WHO) (≥5% of total energy/day) and the American Heart Association statement (AHA) (≥25 g/day).

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Objective: To investigate whether structural aspects of primary care units (PCUs) and the work processes of primary care teams are associated with the rate of hospitalizations for primary care-sensitive conditions (HPCSC) in children younger than 5 years of age in Brazil.

Method: For this longitudinal ecological study, secondary data were obtained from the Brazilian Hospital Information System and from three cycles of the National Program for Access and Quality Improvement in Primary Care (PMAQ-AB) (2012, 2014, 2017/2018). The analysis included 42 916 PCUs.

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Aim: To investigate pathways between unhealthy and healthy dietary patterns and periodontitis in adolescents (18-19 years of age).

Materials And Methods: This population-based study (n = 2515) modelled direct and mediated pathways (via biofilm and obesity) from patterns of healthy diet (fruits, fibre, vegetables, and dairy) and unhealthy diet (sugars, snacks, and salty/fast foods) with initial periodontitis (bleeding on probing [BoP], probing depth [PD] ≥ 4 mm, clinical attachment loss [CAL] ≥ 4 mm), moderate periodontitis (BoP, PD ≥ 5 mm, and CAL ≥ 5 mm), and European Federation of Periodontology and the American Academy of Periodontology (EFP-AAP) periodontitis definitions, adjusting for sex, socio-economic status, smoking, and alcohol, through structural equation modelling (α = 5%).

Results: Higher values of healthy diet were associated with lower values of initial periodontitis (standardized coefficient [SC] = -0.

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Objectives: This study aimed to analyse the relationship between adverse pregnancy outcomes (APO) and occlusal traits in the primary dentition, checking for different mediation paths.

Setting And Sample Population: Children evaluated at birth (T1), between 12 and 24 months (T2), and between 24 and 36 months (T3) were included. Two hundred and seventeen children who participated in T1 and T2 were randomly selected to perform the occlusion examination.

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Background: Maternal hyperglycemia, periodontitis, and adverse gestational outcomes are important health problems. The present study investigated the hypothesis that periodontitis and the glycemic level of mothers may have opposing influences on birth weight (BW). This study evaluated the effect of high glycemic levels, albeit within the normal range, on the association between periodontitis and low birth weight (LBW).

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This article aims to assess whether alterations of oral functions (AOF) are associated with malocclusion (MO)'s type and severity. Cross-sectional study of a representative sample of 332 adolescents aged 12 years in São Luís-MA, Northeastern Brazil. MO criteria included Angle's classification, Dental Aesthetic Index, and other morphological problems.

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Objective: This study evaluated the influence of different mechanical and chemical surface treatments alone and combined with silane on the bond strength (BS) of glass fiber posts (GFPs) using self-adhesive resin cement.

Methods: Eighty-four single-rooted bovine teeth (six groups,  = 14) were submitted to BS analysis after GFP cementation. The treatments applied in the studied groups were no surface treatment (control), silane (S), 24% hydrogen peroxide (PER), 24% hydrogen peroxide and silane (PER + SIL), blasting with 50 m aluminum oxide particles (BLAST), and blasting with 50 m aluminum oxide particles and silane (BLAST + SIL).

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Introduction: The brain-derived neurotrophic factor (BDNF) and neural growth factor (NGF) are widely expressed in the brain and play an important role in neuroplasticity, neurogenesis, and increased neuronal connections. Previous studies have shown that reduced serum levels of these proteins are associated with disorders in human sleep.

Objective: Current study evaluates the prevalence in adolescents of excessive daytime sleepiness (EDS) and sleep quality, and analyzes the influence of these factors on BDNF and NGF serum levels.

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Aim: To evaluate the association between low bone mineral density (BMD) and severe periodontitis at the end of the second decade of life.

Materials And Methods: This population-based study analysed 2032 youngers (18-19 years old) of the RPS cohort. BMD of lumbar spine (BMD-LS) and of the whole body (BMD-WB) were assessed by dual x-ray emission densitometry.

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This study aimed to analyze the association of socioeconomic factors with the prevalence of dental caries in adolescents from São Luís, Maranhão, Brazil, to answer whether social inequalities persist in distributing this disease. This is a cross-sectional study nested in a prospective cohort. We included 2,413 adolescents aged 18-19 years evaluated in the 2016 second follow-up.

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Objective: To assess the structure of primary health care centers (PHCCs) and the work process of primary care teams in child care in Brazil.

Methods: This was an ecological study with data from the three cycles of the Program for Primary Health Care Access and Quality Improvement 2012-2018, by states and regions. Seven structural and thirteen procedural indicators were analyzed.

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Background: Human papillomavirus (HPV) has been associated with certain types of oropharyngeal cancers and yet, the level of knowledge that dental professionals and the lay public have in terms of HPV transmission, oral sexual activities, and oral cancer development needs exploration. The aim of this study was to assess the knowledge held by practicing dental professionals as well as the lay public regarding Human Papillomavirus (HPV) transmission through oral sex and subsequent oropharyngeal cancer development.

Methods: Textual data were collected from a public forum with dental professionals in.

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