Publications by authors named "Claudia Mannino"
Article Synopsis
- * Two compounds were found to have in vitro inhibitory effects similar to a known inhibitor, pepstatin A, and were as effective as fluconazole in treating vaginal candidiasis.
- * These compounds remained effective against a strain of Candida albicans that was resistant to fluconazole, supporting the idea that SAP2 could be a target for creating new antifungal drugs.
Starting from 3-aza-6,8-dioxa-bicyclo[3.2.1]octane scaffold (BTAa) a virtual library of molecules was generated and screened in silico against the crystal structure of the Human Macrophage Metalloelastase (MMP-12).
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