Examining for an association between candidate gene polymorphisms in the metabolic syndrome components on excess weight and adiposity measures in youth: a cross-sectional study.

Background: A polymorphism in a gene may exert its effects on multiple phenotypes. The aim of this study is to explore the association of 10 metabolic syndrome candidate genes with excess weight and adiposity and evaluate the effect of perinatal and socioeconomic factors on these associations.

Methods: The anthropometry, socioeconomic and perinatal conditions and 10 polymorphisms were evaluated in 1081 young people between 10 and 18 years old.

Cardio-metabolic parameters are associated with genetic admixture estimates in a pediatric population from Colombia.

Background: There are different genetic patterns for cardio-metabolic parameters among different populations. Additionally, it has been found that ancestral genetic components (the proportion of Amerindian, European and African) in admixed Latin American populations influence an individual's susceptibility to cardio-metabolic disorders. The aim of this study was to evaluate the effect of ancestral genetic composition on a series of cardio-metabolic risk factors in a young admixed population from Colombia.

Variant in CAPN10 gene and environmental factors show evidence of association with excess weight among young people in a Colombian population.

Unlabelled: Introduction : Obesity results from interaction between genetic and environmental risk factors.

Objective: To evaluate the effect of three gene variants and environmental factors on obesity and overweight in young people aged 10 to 18 years in a Colombian population.

Materials And Methods: A total of 424 subjects were selected and separated into three groups for a cross-sectional study; 100 obese and 112 overweight subjects were matched with 212 normal-weight controls.

Variations in the prevalence of metabolic syndrome in adolescents according to different criteria used for diagnosis: which definition should be chosen for this age group?

Background: Despite the increasing prevalence of metabolic syndrome in adolescents, there is no consensus for its diagnosis.

Methods: A cross-sectional study was conducted to compare the prevalence of metabolic syndrome in adolescents by different definitions, evaluate their concordance, and suggest which definition to apply in this population. A total of 851 adolescents between 10 and 18 years of age were evaluated.

[Environmental risk factors and metabolic syndrome components in overweight youngsters].

Introduction: The environmental risk factors such as food intake and physival activity, are determinants in the etiology of metabolic syndrome in overweight adolescents.

Objective: To explore the association between environmental risk factors and components presence of metabolic syndrome in overweight youngsters in Medellín.

Materials And Methods: Adolescents between the ages of 10 and 18 were selected for a cross sectional study.