Publications by authors named "Claudia M Baumann"
Human amniotic membrane (HAM) has been used as a biomaterial in various surgical procedures and exceeds some qualities of common materials. We evaluated HAM as wound dressing for split-thickness skin-graft (STSG) donor sites in a swine model (Part A) and a clinical trial (Part B). Part A: STSG donor sites in 4 piglets were treated with HAM or a clinically used conventional polyurethane (PU) foil (n = 8 each).
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- Antimicrobial peptides (AMP) are crucial for protecting epithelial surfaces from harmful microorganisms, with significant differences noted in their expression between oral and extraoral tissues.
- Research utilizing real-time PCR, immunohistochemistry, and western blot techniques demonstrated that hBD-1, hBD-2, hBD-3, and psoriasin are expressed more in the oral mucosa than in skin, suggesting a stronger protective role in the mouth.
- Findings indicate potential for developing new treatments based on AMP derivatives, particularly targeting the variances in their expression levels between these two types of epithelium.
We report a case of a patient who developed clinical symptoms of sticky platelet syndrome (SPS) during free microvascular flap transplantation, following resection of an oral tumor. Multiple arterial thromboses of two free tissue transfers occurred as a probable result of SPS. Diagnosis and treatment of the various forms of SPS are described.
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