Publications by Claudia L Pena Murillo

Publications by authors named "Claudia L Pena Murillo"

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Spectral clustering of microarray data elucidates the roles of microenvironment remodeling and immune responses in survival of head and neck squamous cell carcinoma.

Johanna K Thurlow Claudia L Peña Murillo Keith D Hunter Francesca M Buffa Shalini Patiar

J Clin Oncol

June 2010

Purpose: To identify functionally related prognostic gene sets for head and neck squamous cell carcinoma (HNSCC) by unsupervised statistical analysis of microarray data.

Patients And Methods: Microarray analysis was performed on 14 normal oral epithelium and 71 HNSCCs from patients with outcome data. Spectral clustering (SC) analysis of the data set identified multiple vectors representing distinct aspects of gene expression heterogeneity between samples.

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- Claudia L Pena Murillo focuses on the application of statistical analysis techniques, particularly spectral clustering, to explore gene expression patterns in cancer research.
- Her recent work investigates the prognostic gene sets associated with head and neck squamous cell carcinoma (HNSCC), highlighting the influence of microenvironment remodeling and immune responses on survival outcomes.
- The findings from her research suggest that distinct gene expression profiles can be identified in HNSCC, which may contribute to better understanding and potential targeted therapies for the disease.

Publications by authors named "Claudia L Pena Murillo"

Spectral clustering of microarray data elucidates the roles of microenvironment remodeling and immune responses in survival of head and neck squamous cell carcinoma.

Synopsis of recent research by authors named "Claudia L Pena Murillo"