Publications by authors named "Claudia Kuemmerle-Fraune"

Background: Knowledge about primary hypoadrenocorticism coexisting with immune-mediated thyroiditis (Schmidt's syndrome) in dogs is limited.

Objective: To evaluate thyroid function in dogs with naturally occurring hypoadrenocorticism before and during treatment.

Animals: Sixty-six client-owned dogs.

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Background: Lowering the dose of desoxycorticosterone pivalate (DOCP) for the treatment of dogs with primary hypoadrenocorticism (PH) decreases costs and could lead to increased owner motivation to treat their affected dogs.

Objective: To evaluate the efficacy of a low-dose DOCP treatment protocol in dogs with PH.

Animals: Prospective study, 17 client-owned dogs with naturally occurring PH (12 newly diagnosed, 5 previously treated with fludrocortisone acetate [FC]).

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Background: The ideal method for monitoring trilostane therapy in dogs with hypercortisolism is still open to debate. Recently, determination of the pre-trilostane (prepill) cortisol concentration has been proposed to be more repeatable than either post-trilostane or post-ACTH cortisol. The aim of this study was to compare two prepill cortisol concentrations in dogs with hypercortisolism during trilostane therapy.

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Background: Correlation of plasma fibrinogen concentration (fibrinogen ) with rotational thromboelastometry (ROTEM) parameters has not been investigated in dogs.

Objectives: To determine the correlation between plasma coagulation tests and fibrinogen with ROTEM parameters and to evaluate their ability to predict bleeding in dogs.

Animals: Ninety-seven dogs with concurrent determination of fibrinogen and fibrin polymerization test (FIBTEM) analysis.

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