Background: Little is known about homeless patients in intensive care units (ICUs).
Objectives: To compare clinical characteristics, treatments, and outcomes of homeless to non-homeless patients admitted to four ICUs in a large inner-city academic hospital.
Methods: 63 randomly-selected homeless compared to 63 age-, sex-, and admitting-ICU-matched non-homeless patients.
Sepsis is a leading cause of death worldwide. Current treatment modalities remain largely supportive. Intervention strategies focused on inhibiting specific mediators of the inflammatory host response have been largely unsuccessful, a consequence of an inadequate understanding of the complexity and heterogeneity of the innate immune response.
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