Publications by authors named "Claudia Carsetti"
Article Synopsis
- * The study reveals the role of the Cullin-4-RING E3 ubiquitin ligase complex (CRL4) in regulating spastin stability by preventing its degradation, which could lead to potential therapeutic strategies.
- * Using a Drosophila model, researchers demonstrated that inhibiting the CRL4 complex increased spastin levels and improved symptoms, suggesting that blocking this pathway could help in treating SPG4-HSP.
