Heterologous expression and biochemical characterisation of the recombinant β-carbonic anhydrase (MpaCA) from the warm-blooded vertebrate pathogen .

Warm-blooded animals may have on healthy skin, but changes in the skin microenvironment or host defences induce this opportunistic commensal to become pathogenic. Malassezia infections in humans and animals are commonly treated with azole antifungals. Fungistatic treatments, together with their long-term use, contribute to the selection and the establishment of drug-resistant fungi.

Inhibitory Effects of Sulfonamide Derivatives on the -Carbonic Anhydrase (MpaCA) from , a Commensal, Pathogenic Fungus Present in Domestic Animals.

Fungi are exposed to various environmental variables during their life cycle, including changes in CO concentration. CO has the potential to act as an activator of several cell signaling pathways. In fungi, the sensing of CO triggers cell differentiation and the biosynthesis of proteins involved in the metabolism and pathogenicity of these microorganisms.