Publications by authors named "Claudia A Vilchis-Nestor"
Article Synopsis
- The β subunit of Na, K-ATPase, also known as AMOG, plays a key role in the adhesion of astrocytes to neurons and influences neuronal development but its interaction mechanisms have not been fully understood.
- Research conducted through various assays indicates that the β subunit can form stable dimers between adjacent cells, implying that it functions as a homophilic adhesion molecule.
- Experiments show that transfected CHO fibroblasts exhibit increased adhesion and aggregation in a manner that relies on N-glycans, indicating that the β subunit interacts with itself on the surface of different cell types.
Adhesion is a crucial characteristic of epithelial cells to form barriers to pathogens and toxic substances from the environment. Epithelial cells attach to each other using intercellular junctions on the lateral membrane, including tight and adherent junctions, as well as the Na,K-ATPase. Our group has shown that non-adherent chinese hamster ovary (CHO) cells transfected with the canine β subunit become adhesive, and those homotypic interactions amongst β subunits of the Na,K-ATPase occur between neighboring epithelial cells.
View Article and Find Full Text PDFThe introduction of species into new ecosystems, especially in small and isolated regions such as islands, offers an excellent opportunity to answer questions of the evolutionary processes occurring in natural conditions on a scale that could never be achieved in laboratory conditions. In this study, we examined the Mexican red rump tarantula Brachypelma vagans Ausserer (Mygalomorphae: Theraphosidae), a species that was introduced to Cozumel Island, Mexico, 40 years ago. This introduction provides an exceptional model to study effects such as morphological variation between island populations and those on the mainland in open habitats facing the island.
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