Motor score of the Unified Parkinson Disease Rating Scale as a good predictor of Lewy body-associated neuronal loss in the substantia nigra.

Background: How well the motor symptoms assessed by the motor section of the Unified Parkinson Disease Rating Scale (UPDRS3) reflect the neuronal loss observed in the substantia nigra is not known.

Objective: To study the relationships among the motor symptoms assessed by the UPDRS3, Lewy body-associated neuronal loss in the substantia nigra, and duration of disease.

Design: Longitudinal, prospective, clinicopathological study.

Risk factors for deep vein thrombosis in inpatients aged 65 and older: a case-control multicenter study.

Objectives: To identify independent risk factors of symptomatic deep vein thrombosis (DVT) in geriatric inpatients and to define high-risk patients likely to benefit from preventive treatment.

Design: Hospital-based case-control multicenter study with prospective data collection.

Settings: Geriatric university hospitals with long-, intermediate-, and short-term care facilities.