Reaction times as a measure of uncertainty.

In this article, a method is presented to analyse relationships between detection or discrimination frequencies and reaction times in psychophysical tasks. It is shown in three empirical data sets that reaction time decreases as a linear function of the absolute value of the logit transforms of the response probabilities. Such a function stresses the characteristic uncertainty associated with subjects' responses and the relation between their response parameters and the response criterion used by the subjects.

Evolution of genes and genomes on the Drosophila phylogeny.

Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution.

Visual representations of dynamic actions from static pictures.

We investigated how subjects used their knowledge of biomechanical constraints when judging whether different items were in balance or in the process of falling, as a function of their angle of slant. In the first experiment, the stimuli were pictures of postures of a human body, of a wooden mannequin, and of a skeleton. The results show that for these 3 items, fall responses appeared for a smaller slant angle for a backward slant than for a forward one.

Speed of response initiation in a time-to-contact discrimination task reflects the use of eta.

Avoiding collisions and making interceptions seem to require an organism to estimate the time that will elapse before an object will arrive to the point of observation (time-to-contact). The most outstanding account for precise timing has been the tau hypothesis. However, recent studies demonstrate that tau is not the only source of information in judging time-to-contact.

Modification of a reactive cysteine explains differences between rasburicase and Uricozyme, a natural Aspergillus flavus uricase.

Urate oxidase is used in humans for the control of uric acid in patients receiving chemotherapy. Rasburicase (Fasturtec/Elitek), a recombinant urate oxidase expressed in Saccharomyces cerevisiae, was compared with Uricozyme, the natural enzyme produced by Aspergillus flavus. Rasburicase has a higher purity as demonstrated by SDS/PAGE and chromatographic analysis and a better specific activity.

On the delay in processing high spatial frequency visual information: reaction time and VEP latency study of the effect of local intensity of stimulation.

Saleh and Bonnet [Fechner Day 98, p. 344] have shown that, upon parafoveal stimulation and up to 6.5 c/deg, reaction time (RT) is a function of grating contrast multiplied by grating period.