Publications by authors named "Clauber Tieppo"
Article Synopsis
- Musculoskeletal disorders are major global health issues, causing disability in people of all ages due to both aging and injuries, leading to significant emotional and economic consequences.
- Current treatments, both pharmacological and non-pharmacological, offer limited long-term pain relief and don't effectively repair damaged tissues.
- Novel therapies like bone marrow aspirate (BMA) show promise due to their rich cellular components that aid in tissue regeneration and modulate inflammatory responses, although the underlying regenerative mechanisms are still not completely understood.
Objective: To compare topical intravenous tranexamic acid (TA) in total knee arthroplasty regarding blood loss and transfusion.
Methods: Ninety patients were randomized to receive TA intravenously (20 mg/kg in 100 mL of saline; group IV), topically (1.5 g in 50 mL of saline, sprayed over the operated site, before release of the tourniquet; topical group), or intravenous saline (100 mL with anesthesia; control group).
Background: Tranexamic acid (TXA) is widely used in orthopedic surgery to reduce perioperative bleeding. Since TXA inhibits fibrinolysis, there is concern that it may increase the risk of thromboembolic events.
Objectives: To verify the prevalence of deep venous thrombosis (DVT) in patients receiving TXA during total knee arthroplasty and to compare topical with intravenous administration of the drug.