Publications by authors named "Clark Wu"
Article Synopsis
- Metabolic syndrome is increasingly common, particularly among middle-aged people, despite efforts to prevent it.
- This study investigates the impact of a high-fat diet on middle-aged mice, focusing on how it affects cognitive function and explores the role of voluntary exercise in improving both physical and mental health.
- Results show that voluntary exercise enhances learning and memory while fixing gene expression related to energy metabolism in the brain, suggesting it could be a valuable therapy for metabolic syndrome.
Alzheimer's disease (AD) is by far the most prevalent neurodegenerative disease of aging and is a major burden for patients, caregivers, and the overall health care system. The complexity of AD pathophysiology and the lack of deep understanding of disease mechanisms impeded the development of AD therapy. Currently approved treatments for AD only modestly improve cognitive function but do not modify disease course.
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