Publications by authors named "Clark Mbou-Boutambe"

The objective of this were conducted to elucidate spatiotemporal variations in malaria epidemiology in Gabon since 1980. For that, five databases, were used to collect and identify all studies published between 1980 and 2023 on malaria prevalence, antimalarial drug resistance, markers of antimalarial drug resistance and insecticide resistance marker. The findings suggest that Gabon continues to face malaria as an urgent public health problem, with persistently high prevalence rates.

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Article Synopsis
  • - Caliciviruses and astroviruses are major causes of non-bacterial foodborne illnesses and gastroenteritis in humans, with rodents being key hosts for these viruses and many zoonotic pathogens that can affect humans.
  • - A study screened 245 rodent intestine samples for these viruses, finding no caliciviruses but detecting astroviruses in 18 samples, specifically from the Rattus rattus species.
  • - Phylogenetic analysis revealed that the detected astroviruses are closely related to strains found in Gabon, Kenya, and Asia, indicating that transportation methods may promote the spread of these viruses through rodent populations.
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Coronaviruses (CoVs, ) are a diverse group of viruses that infect mammals, birds, and fish. Seven CoVs infect humans, among which Severe Acute Respiratory Syndrome CoVs-1 and -2 and Middle East respiratory syndrome CoVs have shown how they can impact global health and the economy. Their spillover from bats-the natural reservoir-to humans has required intermediary hosts.

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Control and treatment programs (CDTI) have been set up nationally in all endemic countries to overcome the impact of onchocerciasis on the affected populations. However, Gabon must still succeed in setting up real onchocerciasis control programs. Here, various database articles have been used to provide the scientific community with a summary document showing the mapping of this disease in Gabon.

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Article Synopsis
  • * A review of 7543 articles resulted in the inclusion of 42 studies spanning 91 years and identified 41 mosquito species in Gabon's diverse environments, particularly focusing on the Gambiae, Nili, Funestus, and Moucheti groups.
  • * The presence of malaria vectors in both sylvatic and urban settings indicates a complex relationship that could influence malaria transmission, highlighting the need for further entomological research to enhance vector control strategies in Gabon.
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