The study compares two rapid diagnostic tests, BL-RED and β-LACTA, for detecting multidrug-resistant Enterobacterales from positive blood cultures within one hour.
Both tests showed high specificity and positive predictive values but varied in sensitivity, with BL-RED and β-LACTA achieving 45.7% and 52.2%, respectively, in detecting third-generation cephalosporin resistance.
While effective for most Ambler class A-producing Enterobacterales, both tests struggled with detecting AmpC overexpressed and Ambler class B-producing strains, highlighting the need for further testing when results are negative.