Effects of changing ions on the crystal design, non-covalent interactions, antimicrobial activity, and molecular docking of Cu(II) complexes with a pyridoxal-hydrazone ligand.

The present work reports the influence of the presence of different ions (Cl, Br, NO , or SO ) on the formation and proprieties of Cu(II) complexes with pyridoxal-benzoylhydrazone (PLBHZ). Four new complexes were successfully synthesized, [CuCl(PLBHZ)] (1), [CuBr(PLBHZ)] (2), [CuCl(PLBHZ)HO]⋅NO⋅HO (3), and [CuSO(PLBHZ)HO]⋅3HO (4), and characterized by spectroscopic and physicochemical methods. A single-crystal X-ray study reveals the Schiff base coordinated to the metal center tridentate by the -donor system, resulting in distorted square pyramidal coordination geometries.