Publications by authors named "Clarissa Jungerius"
Aim/objective: Indicating how community participation transfers to application within the nursing learning and working context.
Background: Preparing nurses to drive advances in health care requires the integration of working and learning. Learning communities are therefore recommended to connect students, educational programs and health care organizations.
The fibrinous exudate of a wound or tumor stroma facilitates angiogenesis. We studied the involvement of RGD-binding integrins during tube formation in human plasma-derived fibrin clots and human purified fibrin matrices. Capillary-like tube formation by human microvascular endothelial cells in a 3D plasma-derived fibrinous matrix was induced by FGF-2 and TNF-alpha and depended largely on cell-bound u-PA and plasmin activities.
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- Endometrial angiogenesis is crucial for a receptive endometrium, and the study investigates the role of membrane type-3 metalloproteinase (MT3-MMP) and other MT-MMPs in this process.
- The research involved analyzing RNA/protein expressions of six MT-MMPs in cultured endometrial cells and using immunohistochemistry on human endometrial sections to examine in vivo relationships with vascularization.
- Findings revealed that MT-MMPs are expressed in various endometrial cell types in a cycle-dependent manner, particularly correlating MT2-, MT3-, and MT4-MMP expressions with vascularization during different phases of the menstrual cycle, reinforcing earlier in vitro data on their role in angiogenesis.