Publications by authors named "Clariano Pires DE Oliveira Neto"
Predictors of Hepatic Fibrosis in Type 2 Diabetes Patients with Metabolic-Dysfunction-Associated Steatotic Liver Disease.
Biomedicines
November 2024
Background/objectives: Approximately 25% of the world's population and more than 60% of patients with type 2 diabetes (T2D) have metabolic-dysfunction-associated steatotic liver disease (MASLD). The association between these pathologies is an important cause of morbidity and mortality in Brazil and worldwide due to the high frequency of advanced fibrosis and cirrhosis. The objective of this study was to determine the epidemiologic and clinical-laboratory profile of patients with T2D and MASLD treated at an endocrinology reference service in a state in northeastern Brazil, and to investigate the association of liver fibrosis with anthropometric and laboratory measurements.
View Article and Find Full Text PDFRelationship Between C-Peptide Levels, Clinical Features, and Serum Data in a Brazilian Type 1 Diabetes Population with Large Variations in Genomic Ancestry.
Int J Mol Sci
October 2024
Article Synopsis
- - Type 1 diabetes (T1D) is a chronic condition where the immune system attacks beta cells in the pancreas that produce insulin; C-peptide, released alongside insulin, is a helpful marker for evaluating pancreatic function due to its longer lifespan in the body.
- - A study involving 95 T1D patients focused on the levels of C-peptide and its relationship with factors like age, revealing that nearly 30% had some remaining insulin secretion, primarily linked to their age at diagnosis.
- - No significant differences were found in metabolic control or microvascular complications based on C-peptide levels, and it was noted that ancestry did not affect residual C-peptide function; future research should explore additional factors like HLA and pancreatic auto
Healthy lifestyle and genomic ancestry related to good glycemic control in type 1 diabetes patients from Northeastern Brazil: a hierarchical analysis.
Front Endocrinol (Lausanne)
October 2023
Introduction: This study aimed to investigate the sociodemographic factors, dietary adherence, regular physical activity, and genomic ancestry percentage associated with good glycemic control in Brazilian patients with type 1 diabetes (T1D) using a hierarchical approach.
Methods: A cross-sectional study was conducted in 152 T1D patients. Glycated hemoglobin (HbA1C) levels were measured to evaluate the glycemic control status (good, moderate, or poor).
Article Synopsis
- During the COVID-19 pandemic, there was a notable increase in cases of precocious puberty among girls, prompting a study at a Pediatric Endocrinology Clinic in Brazil.
- The study compared 22 girls who started puberty during the pandemic to 33 who started before, examining various clinical and anthropometric factors.
- Findings revealed that girls who began puberty during the pandemic had higher weight Z-scores, lower ovarian volume, and shorter time intervals between parental notice and diagnosis of puberty, indicating a potential impact of the pandemic on puberty timing.
A growing proportion of oropharyngeal squamous cell carcinomas (OPSCC) are associated with infection by high-risk human papillomavirus (HPV). For reasons that remain largely unknown, HPV+OPSCC is significantly more common in men than in women. This study aims to determine the incidence of OPSCC in male and female HPV16-transgenic mice and to explore the role of female sex hormone receptors in the sexual predisposition for HPV+ OPSCC.
View Article and Find Full Text PDFBackground/aim: Head-and-neck squamous cell carcinoma (HNSCC) is the fifth most common cancer in the world and human papillomavirus (HPV) is an important risk factor for this neoplasm. Recent studies showed an association between sex hormone receptors and pathogenesis and/or prognosis in patients with HNSCC. The aim of this study was to clarify the expression patterns of sex hormone receptors in HPV-positive and HPV-negative HNSCC and their associations with tumour biopathology and biological behaviour.
View Article and Find Full Text PDFHuman Papillomavirus and Coronary Artery Disease in Climacteric Women: Is There an Association?
ScientificWorldJournal
January 2020
Article Synopsis
- Cardiovascular diseases are major global health issues, and recent research suggests that certain viruses, like HPV, may contribute to the risk of developing coronary artery disease (CAD), especially in women.
- A study involving 52 climacteric women found that a significant number of those with CAD tested positive for HPV, indicating a strong link between HPV infection and CAD risk.
- The findings suggest that HPV-positive women have a higher likelihood of having CAD, particularly with high-risk HPV types, but further research is necessary to explore the underlying mechanisms of this association.