Publications by authors named "Clare Marie Isacke"

Article Synopsis
  • - Tissue fibrosis and reduced blood vessel density are major issues in kidney disease, with CD248 being a protein linked to these problems in cells of damaged kidneys.
  • - In a study using a kidney injury model, researchers found that mice without the CD248 gene showed less fibrosis and reduced blood vessel loss after injury, possibly due to changes in how cells called pericytes behaved.
  • - The findings suggest that targeting CD248 could help prevent kidney damage by altering the activity of harmful stroma cells, offering a potential therapeutic approach for kidney disease.
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