Publications by authors named "Clare M Burton"
Background: This study used data from a large UK outbreak investigation, to develop and validate a new case definition for hypersensitivity pneumonitis due to metalworking fluid exposure (MWF-HP).
Methods: The clinical data from all workers with suspected MWF-HP were reviewed by an experienced panel of clinicians. A new MWF-HP Score was then developed to match the "gold standard" clinical opinion as closely as possible, using standard diagnostic criteria that were relatively weighted by their positive predictive value.
Article Synopsis
- - The study aimed to evaluate how workplace exposures contribute to the risk of chronic obstructive pulmonary disease (COPD) in a community with many industrial jobs in Sheffield, U.K.
- - Researchers collected data from 4,000 residents over 55 and found that exposure to vapours, gases, dusts, and fumes (VGDF) significantly increased the risk of COPD, with notable population attributable risk values indicating a strong association.
- - This study supports existing evidence linking occupational factors to COPD, demonstrating that both self-reported exposure and a job exposure matrix (JEM) method highlight risks in an industrial community.
Article Synopsis
- A systematic review examined demographic risk factors for respiratory disease outbreaks linked to water-based metalworking fluids (MWFs) through published investigation reports.
- The review analyzed 35 articles on 27 outbreaks, mostly in the US, particularly from large manufacturing plants, and found no consistent hygiene-related risk factors.
- Workers exposed to MWFs were more likely to report respiratory issues, and some studies indicated a connection between extrinsic allergic alveolitis (EAA) and immune responses to microbial contaminants.