Publications by authors named "Clare Labiran"
Chlamydia trachomatis is the most common sexually transmitted infection (STI) in England. Our objective was to perform a detailed survey of the molecular epidemiology of C. trachomatis in the population of Southampton UK attending the genitourinary medicine clinic (GUM) to seek evidence of sexual network activity.
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- The study investigated the distribution of Chlamydia trachomatis genotypes among men who have sex with men (MSM) at the Brighton GUM Clinic, focusing on correlations with HIV status and other clinical variables.
- Out of 1809 MSM participants, 112 (6.2%) tested positive for rectal Chlamydia, revealing 66 different genotypes with significant differences between HIV-negative and HIV-positive men.
- The findings showed a higher diversity of C. trachomatis strains within this population compared to other cities, with prevalent genotypes including G, E, and D, and distinct clusters of genotypes associated with HIV status.
We aimed to evaluate the stability of the Chlamydia trachomatis multi locus VNTR analysis (MLVA-ompA) and multi sequence typing (MST) systems through multiple passages in tissue culture. Firstly, we analyzed the stability of these markers through adaptation of C. trachomatis to tissue culture and secondly, we examined the stability of a four-locus MLVA-ompA and a five-locus MST system after multiple passages in tissue culture.
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