Using neuroimaging to identify sex differences in adults with sports-related concussion: a systematic review.

Concussion is a common injury in sports that causes neurological damage, leading to memory loss and difficulty concentrating. Insufficient recovery time may result in significant long-term harm to individuals. Several neuroimaging techniques have been used to understand the pathophysiological changes following concussion, and how long individuals need to recover before returning to play.

Samarium doped titanium dioxide nanoparticles as theranostic agents in radiation therapy.

Purpose: Titanium dioxide nanoparticles (TiO NPs) have been investigated for their role as radiosensitisers for radiation therapy. The study aims to increase the efficiency of these NPs by synthesising them with samarium.

Methods: Samarium-doped TiO NPs (Ti(Sm)O NPs) were synthesised using a solvothermal method.

Reversing the Effects of a Peripheral Nerve Block with Normal Saline: A Randomised Controlled Trial.

Objective: The objective of the present study was to determine whether or not the effects of peripheral nerve block can be reversed by flushing normal saline down a peripheral nerve block catheter following the completion of arteriovenous (AV) fistula surgery.

Methods: In the present study, 38 patients undergoing AV fistula surgery were recruited, and a brachial plexus block with a peripheral nerve catheter was established. Following surgery, the patients were randomised to either the control group or the washout group, where 10 mL of normal saline was flushed down the peripheral nerve catheter at 15-minute intervals for 1 h while the patients were in the postoperative recovery room.

Evaluation of the IAEA-TRS 483 protocol for the dosimetry of small fields (square and stereotactic cones) using multiple detectors.

The IAEA TRS 483 protocol for the dosimetry of small static fields in radiotherapy was used to calculate output factors for the Elekta Synergy linac at the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA). Small field output factors for both square and circular fields were measured using nine different detectors. The "corrected" output factors (ratio of detector readings multiplied by the appropriate correction factor from the protocol) showed better consistency compared to the "uncorrected" output factors (ratio of detector readings only), with the relative standard deviation decreasing by approximately 1% after the application of the relevant correction factors.

Application of the 'Spiking' method to the measurement of low dose radiation (≤ 1Gy) using alanine dosimeters.

Alanine dosimeters are limited in radiotherapy by poor sensitivity at low doses (< 5Gy). A set of alanine dosimeters were 'spiked' with a large dose of radiation, (~30Gy, 6MV X-rays) and additional doses ranging between 0.5 and 10Gy.

Synthesis and cytotoxic activity of N-[(alkylamino)alkyl]carboxamide derivatives of 7-oxo-7H-benz[de]anthracene, 7-oxo-7H-naphtho[1,2,3-de]quinoline, and 7-oxo-7H-benzo[e]perimidine.

7-Oxo-7H-naphtho[1,2,3-de]quinoline-11-carboxamides and analogues were prepared and evaluated for in vitro and in vivo antitumor activity. Chromophore variations included 'deaza' (7-oxo-7H-benz[de]anthracene) and 'diaza' (7-oxo-7H-benzo[e]perimidine) analogues, and side chain variations included chiral alpha-methyl compounds. The naphthoquinolines were the most cytotoxic, with IC(50) values of 5-20 nM, and showed the strongest DNA binding, with high selectivity for G-C rich DNA.