Publications by authors named "Clare Gouldstone"
Article Synopsis
- An independent dosimetry audit for proton therapy delivery is recommended to ensure consistent treatments across different centers; this study outlines a methodology developed through collaboration between MedAustron and the National Physical Laboratory.
- The auditing process involved using phantoms—one homogeneous and one anthropomorphic—dosed with ionization chambers, alanine pellets, and radiochromic films to evaluate treatment accuracy under different scenarios.
- Results showed that measurements using alanine pellets and ionization chambers were consistent, with minimal deviations from predicted doses; the successful application of this audit method at five proton centers suggests it could be valuable for future clinical trial credentialing in proton beam therapy.
Background And Purpose: Assessment of dosimetric accuracy of radiosurgery on different treatment platforms.
Material And Methods: Thirty-three single fraction treatment plans were assessed at thirty centres using an anthropomorphic head phantom with target and brainstem structures. The target being a single irregular shaped target, ~8 cc, 10 mm from the brainstem.
Reference dosimetry in the presence of a strong magnetic field is challenging. Ionisation chambers have shown to be strongly affected by magnetic fields. There is a need for robust and stable detectors in MRI-guided radiotherapy (MRIgRT).
View Article and Find Full Text PDFPurpose: Lack of standardization and inaccurate dosimetry assessment in preclinical research is hampering translational opportunities for new radiation therapy interventions. The aim of this work was to develop and implement an end-to-end dosimetry test for small animal radiation research platforms to monitor and help improve accuracy of dose delivery and standardization across institutions.
Methods And Materials: The test is based on a bespoke zoomorphic heterogeneous mouse and WT1 Petri dish phantoms with alanine as a reference detector.
Background And Purpose: A UK national dosimetry audit was carried out to assess the accuracy of Stereotactic Ablative Body Radiotherapy (SABR) lung treatment delivery.
Methods And Materials: This mail-based audit used an anthropomorphic thorax phantom containing nine alanine pellets positioned in the lung region for dosimetry, as well as EBT3 film in the axial plane for isodose comparison. Centres used their local planning protocol/technique, creating 27 SABR plans.
Background: Rotational IMRT (VMAT and Tomotherapy) has now been implemented in many radiotherapy centres. An audit to verify treatment planning system modelling and treatment delivery has been undertaken to ensure accurate clinical implementation.
Material And Methods: 34 institutions with 43 treatment delivery systems took part in the audit.
Purpose: The aim of the present study is to provide a comprehensive set of detector specific correction factors for beam output measurements for small beams, for a wide range of real time and passive detectors. The detector specific correction factors determined in this study may be potentially useful as a reference data set for small beam dosimetry measurements.
Methods: Dose response of passive and real time detectors was investigated for small field sizes shaped with a micromultileaf collimator ranging from 0.
Purpose: To develop a methodology for the use of a commercial detector array in dosimetry audits of rotational radiotherapy.
Materials And Methods: The methodology was developed as part of the development of a national audit of rotational radiotherapy. Ten cancer centres were asked to create a rotational radiotherapy treatment plan for a three-dimensional treatment-planning-system (3DTPS) test and audited.