Publications by authors named "Clare E Mahon"
Mol Cancer Ther
April 2017
Article Synopsis
- * The study investigated the effects of combining a pan-FGFR inhibitor (BGJ398) with various PI3K inhibitors (GDC-0941, BKM120, BYL719) in FGFR2 endometrial cancer cell lines, revealing strong synergy between BGJ398 and the PI3K inhibitors.
- * Results indicated that the combination therapies led to significant tumor regressions and increased cell death, suggesting that using lower doses of PI3K inhibitors alongside FGFR inhibitors could lead to better therapeutic outcomes for patients with FG
