Publications by authors named "Clara Soyris"
In the version of this article initially published, the penultimate sentence of the abstract included a typographical error ('cxgenes'). The correct word is 'genes'. The error has been corrected in the HTML and PDF version of the article.
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- - N-methyladenosine (mA) is a common modification found on mRNA, and its absence can affect how viruses reproduce through disrupted methylation of viral RNA.
- - Deleting mA 'writer' METTL3 or 'reader' YTHDF2 after viral infection increases interferon-stimulated gene activity, leading to reduced viral propagation via interferon signaling.
- - The study highlights that mA alters the stability of interferon mRNAs, acting as a negative regulator of the interferon response and ultimately aiding viral spread, a mechanism also observed in mice.
We describe six persons from three families with three homozygous protein truncating variants in PUS7: c.89_90del (p.Thr30Lysfs20), c.
View Article and Find Full Text PDFAdenosine (A) to inosine (I) RNA editing is widespread in eukaryotes. In prokaryotes, however, A-to-I RNA editing was only reported to occur in tRNAs but not in protein-coding genes. By comparing DNA and RNA sequences of , we show for the first time that A-to-I editing occurs also in prokaryotic mRNAs and has the potential to affect the translated proteins and cell physiology.
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