Publications by authors named "Clara Schuetz"
Article Synopsis
- The study investigates the use of von Willebrand factor antigen (vWF-Ag) as a non-invasive biomarker to assess complications related to portal hypertension and predict patient outcomes in hepatocellular carcinoma (HCC) after liver resection.
- The research found that vWF-Ag levels were strongly linked to time to recurrence and overall survival, with specific cutoff values indicating significant risk for posthepatectomy liver failure (PHLF) and clinically significant portal hypertension (CSPH).
- Results suggest that measuring vWF-Ag could enhance preoperative risk assessment for patients with resectable HCC, potentially guiding treatment decisions based on identified risk levels.
Recently, von-Willebrand-Factor (vWF) has been shown to correlate with postoperative liver dysfunction (LD). Accordingly, "disintegrin-like metalloprotease with thrombospondin type1 motif" (ADAMTS13) is known to cleave vWF in less active fragments. Thus, we aimed to evaluate the diagnostic potential of ADAMTS13-activity (ADAMTS13-AC) to identify patients with postoperative LD after hepatectomy.
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