Publications by authors named "Clara Gimenez-Roca"
Article Synopsis
- Kawasaki disease is a childhood vasculitis treatable with IVIG, which minimizes heart complications and the Egami score is used to identify patients who may not respond to this treatment, proving effective in Japan but not in other populations.
- A study in Catalonia sought to evaluate the Egami score’s effectiveness on local children with Kawasaki disease, involving a broad patient sample from 33 hospitals over a ten-year period.
- Results showed the Egami score's low sensitivity (26%) means it fails to reliably predict non-responders in this Western Mediterranean population, leading researchers to conclude it is not a useful tool for predicting IVIG resistance there.
Background: Adult patients receiving anti-TNFα drugs are at increased risk of tuberculosis (TB), but studies in pediatric populations are limited, and the best strategy for latent tuberculosis infection (LTBI) screening in this population remains controversial. We describe the prevalence of LTBI prior to anti-TNFα therapy and the long-term follow-up after biological treatment initiation in a cohort of children and adolescents.
Methods: Cohort observational study in children and adolescents receiving anti-TNFα agents in a tertiary-care pediatric hospital.
The aims of the study were to assess efficacy and safety of TNF-alpha antagonists (anti-TNF) in a cohort of patients with juvenile idiopathic arthritis (JIA) who began treatment under 4 years old and to assess relapse rate after methotrexate and/or anti-TNF withdrawal. We made a retrospective charts review of our non-systemic JIA patients treated with anti-TNF under 4 years of age between January 2006 and April 2013. Demographics, epidemiologic, clinical, laboratory data and rate of relapse after treatment withdrawal due to clinical remission were collected.
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