Publications by authors named "Clara Fitzsimons"
Ireland has the second-highest birth rate in Europe and poorly developed perinatal psychiatry services. There are no screening services for antenatal depression and no data available on prevalence rates of depression among women attending the Irish obstetric services. The aim of this study was to assess the prevalence rates of depression during pregnancy in a population sample in Ireland using the Edinburgh Postnatal Depression Scale (EPDS) as a screening tool.
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- The study compared different methods for estimating glomerular filtration rate (GFR) and monitoring kidney disease progression, specifically using creatinine, cystatin, and CKD-EPI equations against (99m)Tc-DTPA scintigraphy in 300 subjects.
- Results showed that CKD-EPI equations had the highest correlation with (99m)Tc-DTPA for GFR measurement, particularly in patients with GFR < 60 mL/min.
- The study concluded that cystatin-based equations were more effective in correlating with (99m)Tc-DTPA across all stages of reduced GFR and that proteinuria had significant associations with cystatin levels.
Background: In chronic kidney disease (CKD), accurate estimation of the glomerular filtration rate (GFR) is mandatory. Gold standard methods for its estimation are expensive and time-consuming. We compared creatinine- versus cystatin C-based equations to measure GFR, employing (99m)Tc-DTPA scintigraphy as the gold standard.
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