Publications by authors named "Clara Feldmann"

Article Synopsis
  • A study assessed a new ultrasound-based algorithm for determining when to remove pancreatic stents placed to prevent post-ERCP pancreatitis, aiming to minimize unnecessary X-ray imaging.
  • Out of 88 patients, the ultrasound approach successfully reduced the need for X-rays by 74%, accurately visualizing stents in 81% of cases but with limited specificity.
  • The authors recommend implementing the ultrasound algorithm with training for experienced personnel due to challenges with visualizing shorter stents.
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Norovirus capsids are icosahedral particles composed of 90 dimers of the major capsid protein VP1. The C-terminus of the VP1 proteins forms a protruding (P)-domain, mediating receptor attachment, and providing a target for neutralizing antibodies. NMR and native mass spectrometry directly detect P-domain monomers in solution for murine (MNV) but not for human norovirus (HuNoV).

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Glycan-protein interactions are highly specific yet transient, rendering glycans ideal recognition signals in a variety of biological processes. In human norovirus (HuNoV) infection, histo-blood group antigens (HBGAs) play an essential but poorly understood role. For murine norovirus infection (MNV), sialylated glycolipids or glycoproteins appear to be important.

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