Publications by authors named "Clara Fabienne Rasoamanamihaja"

Article Synopsis
  • The study aimed to estimate the prevalence of Strongyloides stercoralis infection in four districts of Madagascar, focusing on coastal versus highland areas, where data on strongyloidiasis is limited.
  • Serum and fecal samples were analyzed using real-time PCR and serology, revealing a significantly higher prevalence of infection in coastal districts (20.9% and 35.2%) compared to highland districts (5.6% and 6.1%).
  • The research found a strong association between strongyloidiasis and hookworm infection, which was also linked to factors like male gender and lower education levels, suggesting potential public health interventions are needed in the most affected areas.
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Madagascar is one of the countries with the highest burden of schistosomiasis worldwide. The release from the WHO of the new 2021-2030 neglected tropical disease (NTD) roadmap alongside with the schistosomiasis guidelines sets the ambitious goal of eliminating schistosomiasis as a public health problem worldwide. In Madagascar, implementation barriers exist.

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Introduction: Delivering preventive chemotherapy through mass drug administration (MDA) is a central approach in controlling or eliminating several neglected tropical diseases (NTDs). Treatment coverage, a primary indicator of MDA performance, can be measured through routinely reported programmatic data or population-based coverage evaluation surveys. Reported coverage is often the easiest and least expensive way to estimate coverage; however, it is prone to inaccuracies due to errors in data compilation and imprecise denominators, and in some cases measures treatments offered as opposed to treatments swallowed.

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Background: Schistosomiasis affects more than 800 million people, mostly in sub-Saharan Africa. A baseline sentinel site study was conducted in the Western half of Madagascar to determine the prevalence and intensity of schistosomiasis and soil-transmitted helminth (STH) infections prior to mass drug administration, and to explore the associations between infection and school attendance, and access to water, sanitation and hygiene (WASH) facilities.

Methods: A three-stage, cluster-randomised cross-sectional study was conducted in 29 sentinel sites in October 2015.

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