Publications by authors named "Clara Eleonora Antonello"
Article Synopsis
- MCT8 deficiency is a rare condition affecting thyroid hormone transport in the brain, leading to neurological issues and signs of both peripheral thyrotoxicosis and cerebral hypothyroidism.
- The study evaluated movement disorders (MDs) in 27 patients, identifying hypokinesia as the most common MD, alongside other disorders like dystonia and exaggerated startle reactions.
- Findings suggest that MDs are prevalent in MCT8 deficiency, with hypokinesia often being the main concern, possibly due to thyroid hormones' crucial role in brain development and the function of dopaminergic circuits.
OBJECTIVE In this single-center study the authors investigated the complications occurring before and after the introduction of the new Ascenda intrathecal catheter (Medtronic Inc.) in pediatric patients treated with intrathecal baclofen therapy (ITB) for spasticity and/or dystonia. METHODS This was a retrospective review of 508 children who had received ITB, 416 with silicone catheters in the 13 years between September 1998 and September 2011 and 92 with Ascenda catheters in the 3 years between September 2011 and August 2014.
View Article and Find Full Text PDFBackground: The literature available shows that spasticity in patients with cerebral palsy (CP) is reduced by intrathecal baclofen (ITB) treatment, and various studies suggest that this treatment can also be used in dystonic patients. The aim of the present study was to evaluate dystonia treated with ITB in children with CP.
Methods: Data of 19 patients affected by dystonia as an outcome of infant CP in patients belonging to level V of Gross Motor Function Classification System treated with ITB were collected.