Publications by authors named "Clairoux S"

Background: Chronic opioid use has been documented in up to 20% of patients with traumatic injuries. Hence, we developed the Tapering Opioids Prescription Program for high-risk Trauma (TOPP-Trauma) patients.

Aims: To assess the feasibility and acceptability of TOPP-Trauma, examine the feasibility of the research methods, and describe its potential efficacy in reducing long-term opioid use.

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Article Synopsis
  • Opioid use disorder and related deaths have significantly increased, prompting the development of the Tapering Opioids Prescription Program in Trauma (TOPP-Trauma) to help reduce chronic opioid consumption among trauma patients.
  • The study aims to assess the feasibility of the TOPP-Trauma intervention and its methods through a pilot randomized controlled trial involving 50 high-risk patients, comparing the intervention against an educational pamphlet.
  • By evaluating various parameters like dropout rates and morphine equivalent doses over 6 and 12 weeks, the study seeks to provide insights into the effectiveness of preventive strategies for chronic opioid use in trauma patients.
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No studies have directly compared the key characteristics and outcomes of kidney (KTx) and liver transplantation (LTx) recipients with neutropenia. In this single-center, retrospective, cohort study, we enrolled all adult patients who received a KTx or LTx between 2000 and 2011. Neutropenia was defined as 2 consecutive absolute neutrophil count (ANC) values <1500/mm in patients without preexisting neutropenia.

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