Objective: To evaluate to what extent the modification of corneal asphericity to induce spherical aberration (SA) can improve the depth of focus and to determine whether preoperative adaptive optics assessment (Voptica SL) can predict an optimal SA value for each patient.
Design: Comparative, prospective clinical trial with paired eye control.
Participants: Patients ≥45 years old who are hyperopic from +1.
Purpose: To compare visual and optical outcomes of pupil-centered vs vertex-centered ablation in patients undergoing laser-assisted in situ keratomileusis (LASIK) for hyperopia.
Design: Randomized, double-masked, prospective, single-center trial.
Setting: Institutional practice.