Publications by authors named "Claire Seunes"
Article Synopsis
- The study evaluated the prognostic significance of non-invasive parameters related to ventricular-arterial coupling (VAC) in patients with left ventricular ejection fraction (LVEF) ≥40% after a myocardial infarction (MI).
- Using echocardiography and arterial tonometry, researchers measured VAC parameters during rest and a handgrip test in 374 patients, tracking major adverse cardiovascular events (MACE) over a median of 32 months.
- Results indicated that the PWV/GLS ratio was the most useful parameter for identifying high-risk patients for MACE after MI, suggesting it adds valuable information beyond traditional assessment methods.
Article Synopsis
- The study examines the prognostic significance of myocardial work parameters in patients after experiencing an acute myocardial infarction (AMI).
- A total of 244 patients were monitored for major cardiac events after receiving specialized care, with findings indicating that those who experienced events had worse overall heart function and were generally older.
- Specifically, the global work efficiency (GWE) was identified as a crucial measure, with a GWE below 91% indicating a significantly increased risk for major events, making it a valuable tool for assessing post-AMI patient risk.
Background: Pre-operative myocardial fibrosis and remodeling impact on outcomes after aortic valve replacement (AVR). We aimed at investigating the prognostic impact of preoperative electrocardiographic (ECG) markers of left ventricular (LV) myocardial damage, i.e.
View Article and Find Full Text PDFBoth genetic and environmental factors interact to control left ventricular (LV) remodeling in the context of aortic stenosis (AS). Epicardial adipose tissue (EAT) is a specific visceral adipose tissue with paracrine properties in close contact with the myocardium. We sought to assess determinants of EAT amount and its association with the magnitude and pattern of LV remodeling in patients suffering from severe AS.
View Article and Find Full Text PDFBackground: A relevant morning-afternoon variation in ischemia-reperfusion (IR) insult after cardiac surgery has been demonstrated. We speculated that the biorhythm might also impact systemic reactions involved in acute kidney injury (AKI) following cardiac surgery. We aimed at investigating incidence, determinants and prognostic impact of AKI in a large cohort of patients referred for surgical aortic valve replacement (SAVR) according to surgery time-of-day.
View Article and Find Full Text PDFBackground: On-pump cardiac surgery provokes a predictable perioperative myocardial ischaemia-reperfusion injury which is associated with poor clinical outcomes. We determined the occurrence of time-of-the-day variation in perioperative myocardial injury in patients undergoing aortic valve replacement and its molecular mechanisms.
Methods: We studied the incidence of major adverse cardiac events in a prospective observational single-centre cohort study of patients with severe aortic stenosis and preserved left ventricular ejection fraction (>50%) who were referred to our cardiovascular surgery department at Lille University Hospital (Lille, France) for aortic valve replacement and underwent surgery in the morning or afternoon.