Publications by authors named "Claire S Harper"
Brain Behav Immun Health
July 2023
Article Synopsis
- Estrogens are important hormones for female reproductive health and influence immune responses, particularly during menopause.
- A study involved ovariectomized mice (removal of ovaries for estrogen loss) that were given hormone replacement and then subjected to an immune challenge to assess behavioral changes.
- Findings showed that estrogen loss led to altered social and affective behaviors in mice, indicating a connection between declining estrogen levels, microglial sensitivity in the brain, and increased vulnerability to negative emotional effects.
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