Analysis of Predictive Factors for Successful Vascular Anastomoses in a Sheep Uterine Transplantation Model.

Uterine transplantation is becoming an increasingly realistic therapeutic for uterine infertility. Surgical training on large animal models such as sheep is a prerequisite for establishing a program in humans. The objective of our study was to analyze the predictive factors for successful vascular anastomoses.

-Positive Breast Cancer Patients with Pre-Treatment Axillary Involvement or Postmenopausal Status Benefit from Neoadjuvant Rather than Adjuvant Chemotherapy Plus Trastuzumab Regimens.

Background: No survival benefit has yet been demonstrated for neoadjuvant chemotherapy (NAC) against -positive tumors in patients with early breast cancer (BC). The objective of this study was to compare the prognosis of -positive BC patients treated with NAC to that of patients treated with adjuvant chemotherapy (AC).

Materials And Methods: We retrospectively analyzed disease-free (DFS) and overall survival (OS) in 202 -positive patients treated with NAC and 701 patients treated with AC.