Publications by authors named "Claire Knaus"
JCO Precis Oncol
September 2023
Article Synopsis
- A study explored the prevalence of hereditary factors in renal cell carcinoma (RCC) by analyzing the presence of pathogenic or likely pathogenic (P/LP) germline variants in patients who underwent genetic testing.
- Out of 321 analyzed patients, 13.1% had P/LP variants, with notable mutations found in specific genes, and nearly half of these patients had mutations that could be targeted for treatment.
- The research found that bilateral or multifocal tumors were linked to P/LP variants, but factors like age and family cancer history did not significantly affect genetic testing outcomes, emphasizing the need for better genetic evaluation methods in RCC patients.
