Publications by authors named "Claire J Koppel"

During cardiac development the heart is innervated by the autonomous nervous system. After development, neurons of the autonomic nervous system have limited capacity for growth and regeneration. However, in the past decades, it has become clear that cardiac nerves can regenerate after cardiac damage.

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Article Synopsis
  • The study investigates high-risk characteristics of anomalous coronary arteries originating from the opposite sinus of Valsalva (ACAOS) using computed tomography angiography (CTA) to identify features linked to sudden cardiac death.
  • Researchers evaluated 25 patients to develop a new CTA measurement, called interluminal space (ILS), to distinguish an intramural segment of ACAOS.
  • Results showed that an ILS of less than 0.95 mm is a strong indicator of an intramural segment, achieving 100% sensitivity and 84% specificity for diagnosis.
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Background: Progressive renal insufficiency is frequent in heart failure patients with a left ventricular assist device (LVAD). The optimal strategy for long-term dialysis in LVAD patients and its effect on quality-of-life in these patients remain to be determined.

Case Summary: Our 55-year-old patient with pre-existing renal insufficiency received an LVAD as destination therapy because of advanced ischaemic heart failure.

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In single coronary artery (SCA) anatomy, all coronary tributaries arise from a single ostium, providing perfusion to the entire myocardium. Coronary classification systems can facilitate the description of SCA anatomy. Evaluation of the applicability of Lipton classification and the Leiden Convention coronary coding system in SCA.

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Aims: The Leiden Convention coronary coding system structures the large variety of coronary anatomical patterns; isolated and in congenital heart disease. It is widely used by surgeons but not by cardiologists as the system uses a surgeons' cranial view. Since thoracic surgeons and cardiologists work closely together, a coronary coding system practical for both disciplines is mandatory.

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Background: An anomalous coronary artery is reported in 2% to 23% of patients with tetralogy of Fallot (TOF). Knowledge of coronary anatomy prior to corrective surgery is vital to avoid damage to vessels crossing the right ventricular outflow tract (RVOT). A meta-analysis on the prevalence of anomalous coronary arteries in TOF is lacking to date.

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