Publications by authors named "Claire Geneste"
Article Synopsis
- The study examines kidney transplantation outcomes for patients with renal AA amyloidosis, revealing previously unclear results regarding survival and disease recurrence, mostly based on older data.
- Conducted as a retrospective multicenter cohort study, it analyzed patients who underwent transplantation in France from 2008 to 2018, focusing on factors like age and treatment methods.
- Results indicated high survival rates (94% at 1 year, 85.5% at 5 years) but also significant complications, including infection (55.8%) and acute rejection episodes (27.9%), with a low recurrence rate of amyloidosis (5.8%).
Rationale & Objective: Trials in autosomal dominant polycystic kidney disease (ADPKD) have increased, but their impact on decision making has been limited. Because heterogeneity in reported outcomes may be responsible, we assessed their range and variability in ADPKD trials.
Study Design: Systematic review.
Aim: Patients with autosomal dominant polycystic kidney disease (ADPKD) are at increased risk of premature mortality, morbidities and complications, which severely impair quality of life. However, patient-centered outcomes are not consistently reported in trials in ADPKD, which can limit shared decision-making. We aimed to identify outcomes important to patients and caregivers and the reasons for their priorities.
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