Diagnostic accuracy of 18F-FDG PET/CT for assessing response to radiofrequency ablation treatment in lung metastases: a multicentre prospective study.

Purpose: To assess diagnostic accuracy of (18)F-FDG PET/CT at 3 months for the detection of local recurrence after radiofrequency ablation (RFA) of lung metastases.

Methods: The PET/CT scan at 3 months was compared with a baseline PET/CT scan from a maximum of 2 months before RFA, with the reference standard as recurrence diagnosed by CT during a 12-month follow-up. Local recurrence was diagnosed on the PET/CT scan if lesional uptake was greater than the mediastinal background.

MRI quantification of the role of the reflected pressure wave on coronary and ascending aortic blood flow.

The respective roles of the windkessel effect, which is related to the vessel compliance, and of the returning pressure wave, which is reflected off peripheral resistances, in generating the total diastolic blood flow in the ascending aorta (VT: coronary + flow through the upper part of the ascending aorta) were assessed under physiological conditions. In ten healthy young men (21-30 years), magnetic resonance phase mapping was used to assess non-invasively both blood flow and vessel cross-sectional area (CSA) at the upper part of the ascending aorta. Measurements of blood flow velocities and CSAs were carried out over complete cardiac cycles, with a 30 ms resolution time.