Publications by authors named "Claire Flamens"

Combined lung-liver transplantation is a rare life-saving procedure to treat concomitant end-stage lung and liver failure. In this report, we describe the first published case of single lung and liver transplantation in a cystic fibrosis patient who had previously undergone a pneumonectomy for the treatment of an infected and destroyed right lung. We detail the lung first, sequential transplant procedure and surgical difficulties due to mediastinal shift.

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Objectives: Survival after heart transplantation is steadily improving but primary graft dysfunction (PGD) is still a leading cause of death. Medical management seems useful in mild or moderate PGD, whereas extracorporeal life support (ECLS) could be suggested for severe PGD refractory to conventional treatment. Our aim is to present the results of ECLS for PGD after heart transplantation at a single-centre experience.

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Article Synopsis
  • Septic shock, often complicated by acute kidney injury (AKI), is a major cause of death in critically ill patients, prompting the investigation of high-volume haemofiltration (HVHF) as a potential treatment.
  • The study was a clinical trial involving 140 patients with septic shock and AKI, comparing the effects of HVHF and standard-volume haemofiltration (SVHF) on 28-day mortality over a 96-hour period.
  • Results showed no significant difference in mortality rates between the HVHF group (37.9%) and the SVHF group (40.8%), leading to the conclusion that HVHF does not improve outcomes in these patients and is not recommended for treatment.
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Cardiac resynchronization therapy improves symptoms and survival in chronic heart failure patients, but has been poorly studied in the acute heart failure setting. We report the case of successful cardiac resynchronization therapy in the early postoperative period after cardiac surgery in a patient with left bundle branch block and proven ventricular dyssynchrony.

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Since the first case in 1987, 159 patients underwent heart mechanical assist device as a bridge to transplantation or as potential post transplanted recovery (right ventricular failure or graft failure) or in case of unsuccessful weaning of cardiopulmonary bypass. Survival rate of patients under assist device waiting either for heart transplantation or for functional recovery was 75.4%.

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