Young people with an autism spectrum disorder (ASD) are more likely to have heightened levels of anxiety compared with their typically developing (non-ASD) peers. The reasons for this are poorly understood, and there has been little research investigating the cognitive correlates of anxiety in individuals with ASD. Typically developing youth with anxiety disorders have frequently been found to show an attentional bias toward threatening information.
View Article and Find Full Text PDFObjective: Pulmonary venous pathway obstruction (PVPO) is a serious complication of the atrial switch procedure for transposition of the great arteries (TGA). Redistribution of pulmonary arterial blood flow may make conventional echocardiographic measures of unilateral PVPO difficult to interpret. Previous studies have demonstrated altered arterial flow patterns using phase-contrast magnetic resonance imaging (PC-MRI).
View Article and Find Full Text PDFThe pathogenesis of autoimmune diseases includes a combination of genetic factors and environmental exposures including infectious agents. Infectious triggers are commonly indicated as being involved in the induction of autoimmune disease, with Epstein-Barr virus (EBV) being implicated in several autoimmune disorders. EBV is appealing in the pathogenesis of autoimmune disease, due to its high prevalence worldwide, its persistency throughout life in the host's B lymphocytes, and its ability to alter the host's immune response and to inhibit apoptosis.
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